STXBP3

Across TCGA cell cohorts, STXBP3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,864 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STXBP3-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Neutrophil degranulation, and Golgi vesicle transport. Each is linked with STXBP3 in more than 13 cancer types. Because this analysis shows association rather than direction, both STXBP3-to-partner and partner-to-STXBP3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by STXBP3-low versus STXBP3-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP3→partner) and Y-score (partner→STXBP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Zinc ion import into Golgi lumen →	+0.097	+0.564	.009	.002	3	14
LUNG_NSCLC_LUSC	Neutrophil degranulation →	+0.180	+0.732	<.001	<.001	3	13
CNS	Golgi vesicle transport →	+0.047	+0.455	.001	.002	3	11
BLOOD_Lymphoma	Positive regulation of organelle assembly →	+0.051	+0.932	<.001	<.001	3	11
BLOOD_Myeloma	Presynaptic dense core vesicle exocytosis →	+0.151	+0.977	.001	<.001	3	11
SOFT_TISSUE	Cytosol to Golgi apparatus transport →	+0.115	+0.705	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,864 associations by consensus.

Zinc ion import into Golgi lumen by STXBP3 expression — BONE

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