STXBP2

Across TCGA patient cohorts, STXBP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,820 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STXBP2-associated proteins across cancer lineages are PEAK1_S1036, RBSN_S548, and VAMP8. Each is linked with STXBP2 in more than 3 cancer types. Because this analysis shows association rather than direction, both STXBP2-to-partner and partner-to-STXBP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STXBP2 versus PEAK1_S1036 in GBM, with a Pearson correlation of -0.38.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP2→partner) and Y-score (partner→STXBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PEAK1_S1036 →	-0.541	-0.589	<.001	<.001	3	4
CCRCC	RBSN_S548 →	-0.439	-0.445	<.001	<.001	3	3
GBM	VAMP8 →	+0.964	+0.832	<.001	<.001	3	3
GBM	SNX6_S55 →	+0.898	+0.794	.002	.006	3	3
LUAD	SQSTM1 →	+0.394	+0.295	.007	.004	3	3
CCRCC	STAU2_T95 →	+1.121	+0.475	.009	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,820 associations by consensus.

STXBP2 vs PEAK1_S1036 — GBM

Explore this scatter interactively →