STXBP2

Across TCGA cell cohorts, STXBP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,914 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STXBP2-associated GO terms across cancer lineages are Cytotoxic T cell degranulation, Regulation of myoblast fusion, and T cell mediated cytotoxicity. Each is linked with STXBP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both STXBP2-to-partner and partner-to-STXBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytotoxic T cell degranulation grouped by STXBP2-low versus STXBP2-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STXBP2→partner) and Y-score (partner→STXBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Cytotoxic T cell degranulation →	+0.392	+2.749	<.001	<.001	3	15
OVARY	Regulation of myoblast fusion →	+0.103	+1.803	<.001	<.001	3	12
OVARY	T cell mediated cytotoxicity →	+0.221	+1.368	<.001	<.001	3	12
BONE	Negative regulation of DNA-templated transcription initiation →	+0.103	+2.268	.003	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Negative regulation of mRNA processing →	+0.111	+0.671	<.001	<.001	3	11
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.103	+2.268	.003	.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,914 associations by consensus.

Cytotoxic T cell degranulation by STXBP2 expression — STOMACH

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