STX6

Across TCGA patient cohorts, STX6 protein abundance is significantly associated with the RNA expression of many other genes, with 10,582 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible STX6-associated genes across cancer lineages are FLNC, EEF1AKNMT, and FGF7. Each is linked with STX6 in more than 4 cancer types. Because this analysis shows association rather than direction, both STX6-to-partner and partner-to-STX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STX6 versus FLNC in HNSC, with a Pearson correlation of -0.27.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STX6→partner) and Y-score (partner→STX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	FLNC →	-1.076	-0.174	.005	.006	3	5
LSCC	EEF1AKNMT →	+0.366	+0.282	<.001	<.001	3	4
UCEC	FGF7 →	-1.282	-0.351	.001	.001	3	4
LSCC	DCAF6 →	+0.389	+0.218	<.001	<.001	3	4
BRCA	SIGLEC17P →	-0.731	-0.275	<.001	<.001	3	4
CCRCC	CSDC2 →	-0.815	-0.127	.005	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,582 associations by consensus.

STX6 vs FLNC — HNSC

Explore this scatter interactively →