STX1A

Across TCGA cell cohorts, STX1A RNA expression is significantly associated with the go_rna of many other GO terms, with 4,680 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible STX1A-associated GO terms across cancer lineages are Positive regulation of norepinephrine secretion, SNARE complex disassembly, and Regulation of norepinephrine secretion. Each is linked with STX1A in more than 19 cancer types. Because this analysis shows association rather than direction, both STX1A-to-partner and partner-to-STX1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of norepinephrine secretion grouped by STX1A-low versus STX1A-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX1A→partner) and Y-score (partner→STX1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	Positive regulation of norepinephrine secretion →	+1.485	+2.132	<.001	<.001	3	20
LUNG_SCLC	SNARE complex disassembly →	+0.271	+1.767	<.001	<.001	3	20
SKIN	Regulation of norepinephrine secretion →	+1.566	+1.809	<.001	<.001	3	18
OESOPHAGUS	Positive regulation of catecholamine secretion →	+0.367	+1.757	<.001	<.001	3	16
SOFT_TISSUE	Response to gravity →	+0.362	+1.355	.001	<.001	3	14
OVARY	Synaptic vesicle recycling →	+0.103	+1.497	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,680 associations by consensus.

Positive regulation of norepinephrine secretion by STX1A expression — BLOOD_Leukemia

Explore this box plot interactively →