Q-omics provides the consensus-scored STX18-IT1 profile across patient tissues and cancer cell-line models. STX18-IT1 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in THYM. Additionally, STX18-IT1 RNA expression shows 8,664 significant gene co-expression associations, with the highest sampling consensus in ESCA. Together, these results highlight THYM, and ESCA as cancer lineages where STX18-IT1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes STX18-IT1 survival associations across molecular data types. STX18-IT1 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

STX18-IT1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	15	THYM (33)	view →

This table ranks reproducible STX18-IT1 RNA expression–survival associations across cancer types. High STX18-IT1 expression shows unfavorable associations in THYM, THCA, SARC and READ, but favorable associations in KIRC and CHOL. The THYM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify THYM as the clearest survival context for STX18-IT1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THYM	OS	Tertile	II,III,IV	0.794	1.000	.001	33	view →
THCA	DFS	Tertile	IV	0.075	0.807	<.001	30	view →
KIRC	DFS	Tertile	All	0.851	0.780	.020	25	view →
CHOL	OS	Tertile	All	1.000	0.495	.009	18	view →
SARC	OS	Tertile	All	0.314	0.632	<.001	18	view →
READ	DFS	Tertile	II,III,IV	0.436	0.762	.025	18	view →

Pink = unfavorable, green = favorable. all 15 lineages →

STX18-IT1-THYM (OS)

Kaplan–Meier survival curve for STX18-IT1 RNA expression in THYM: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with STX18-IT1 in patient tissues and cancer cell lines. In patient samples, STX18-IT1 shows the broadest associations at the RNA and protein expression levels, with ESCA recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	8,664	ESCA (4171)	view →
Protein (mass-spec)	7,503	LUAD (2582)	view →