STX16

Across TCGA cell cohorts, STX16 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,951 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STX16-associated GO terms across cancer lineages are Negative regulation of autophagy, Negative regulation of organelle assembly, and Regulation of RNA splicing. Each is linked with STX16 in more than 15 cancer types. Because this analysis shows association rather than direction, both STX16-to-partner and partner-to-STX16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by STX16-low versus STX16-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STX16→partner) and Y-score (partner→STX16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Negative regulation of autophagy →	+0.069	+0.690	<.001	<.001	3	16
OESOPHAGUS	Negative regulation of organelle assembly →	+0.097	+1.359	<.001	<.001	3	16
OESOPHAGUS	Regulation of RNA splicing →	+0.094	+1.254	.001	<.001	3	16
BONE	Promoter clearance during DNA-templated transcription →	+0.137	+0.891	<.001	.001	3	15
BONE	RNA polymerase II promoter clearance →	+0.137	+0.891	<.001	.001	3	15
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.163	+1.228	.005	.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,951 associations by consensus.

Negative regulation of autophagy by STX16 expression — STOMACH

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