Across TCGA patient cohorts, STUM protein abundance is significantly associated with the RNA expression of many other genes, with 1,698 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STUM-associated genes across cancer lineages are GLT1D1, IGF2BP2, and CYTH4. Each is linked with STUM in more than 1 cancer types. Because this analysis shows association rather than direction, both STUM-to-partner and partner-to-STUM results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STUM→partner) and Y-score (partner→STUM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	GLT1D1 →	+0.750	+0.460	<.001	<.001	3	2
GBM	IGF2BP2 →	-1.244	-0.528	<.001	<.001	3	2
COAD	CYTH4 →	+0.710	+0.286	.006	.002	3	1
COAD	LGMN →	+0.834	+0.404	.001	.007	3	1
COAD	SAMHD1 →	+0.823	+0.253	.002	.007	3	1
COAD	DNAJC3 →	+0.533	+0.441	.006	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,698 associations by consensus.

Exploration

STUM survival (RNA) · tumor vs normal (RNA) · all STUM data types