STUB1

Across TCGA pan-cancer cohorts, STUB1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated STUB1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher STUB1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated STUB1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, CCRCC, and UCEC are the cancer types where STUB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.881	0.664	.010	22	view →
CCRCC	DFS	Median	All	0.713	0.908	.008	13	view →
UCEC	DFS	Tertile	All	0.902	1.000	.019	10	view →
LSCC	DFS	Median	III,IV	0.436	0.864	.006	7	view →
HNSC	OS	Quartile	III,IV	0.982	0.759	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

STUB1–PDAC (DFS)

Open the PDAC breakdown →