STUB1

Across TCGA patient cohorts, STUB1 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,211 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible STUB1-associated proteins across cancer lineages are STUB1_S19, PGP, and STUB1_S273. Each is linked with STUB1 in more than 8 cancer types. Because this analysis shows association rather than direction, both STUB1-to-partner and partner-to-STUB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STUB1 versus STUB1_S19 in BRCA, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STUB1→partner) and Y-score (partner→STUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	STUB1_S19 →	+0.962	+0.648	<.001	<.001	3	9
OV	PGP →	+0.494	+0.478	<.001	<.001	3	8
PDAC	STUB1_S273 →	+0.980	+0.299	<.001	<.001	2	9
BRCA	ELOC →	+0.323	+0.601	<.001	<.001	3	7
COAD	JPT2 →	+0.487	+0.328	<.001	<.001	3	7
OV	METTL26 →	+0.632	+0.473	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,211 associations by consensus.

STUB1 vs STUB1_S19 — BRCA

Explore this scatter interactively →