STUB1

Across TCGA patient cohorts, STUB1 mutation is significantly associated with the immune_cell of many other genes, with 5 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STUB1-associated genes across cancer lineages are Sebocytes, CD8+ Tem, and lymphatic Endothelial cells. Each is linked with STUB1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STUB1-to-partner and partner-to-STUB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sebocytes grouped by STUB1-low versus STUB1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STUB1→partner) and Y-score (partner→STUB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Sebocytes →	+0.033	+2.834	.010	.035	3	1
UCEC	CD8+ Tem →	+0.001	+4.896	.006	.036	3	1
UCEC	lymphatic Endothelial cells →	-0.026	-3.116	.049	.020	3	1
UCEC	Neutrophils →	+0.016	+2.166	.001	.021	3	1
UCEC	CLP →	+0.091	+3.212	.008	.010	1	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Sebocytes by STUB1 expression — COAD

Explore this box plot interactively →