STT3B

Across TCGA cell cohorts, STT3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,601 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STT3B-associated GO terms across cancer lineages are Response to hepatocyte growth factor, Chemokine (C-C motif) ligand 21 signaling pathway, and Adiponectin-activated signaling pathway. Each is linked with STT3B in more than 11 cancer types. Because this analysis shows association rather than direction, both STT3B-to-partner and partner-to-STT3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to hepatocyte growth factor grouped by STT3B-low versus STT3B-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STT3B→partner) and Y-score (partner→STT3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Response to hepatocyte growth factor →	+0.167	+0.826	<.001	<.001	3	12
URINARY_TRACT	Chemokine (C-C motif) ligand 21 signaling pathway →	+0.215	+0.976	.001	<.001	3	12
KIDNEY	Adiponectin-activated signaling pathway →	+0.160	+0.881	<.001	<.001	3	11
BLOOD_Myeloma	Ubiquitin-dependent glycoprotein ERAD pathway →	+0.144	+0.499	<.001	.001	3	11
BONE	Protein demannosylation →	+0.101	+0.679	.001	.007	3	11
BONE	Protein alpha-1,2-demannosylation →	+0.101	+0.679	.001	.007	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,601 associations by consensus.

Response to hepatocyte growth factor by STT3B expression — LUNG_SCLC

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