STT3A

Across TCGA cell cohorts, STT3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,808 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible STT3A-associated GO terms across cancer lineages are Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway, Positive regulation of protein exit from endoplasmic reticulum, and Meiotic chromosome condensation. Each is linked with STT3A in more than 13 cancer types. Because this analysis shows association rather than direction, both STT3A-to-partner and partner-to-STT3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway grouped by STT3A-low versus STT3A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STT3A→partner) and Y-score (partner→STT3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway →	+0.211	+0.821	<.001	.003	3	14
KIDNEY	Positive regulation of protein exit from endoplasmic reticulum →	+0.122	+1.285	<.001	.003	3	13
UPPER_AERODIGESTIVE_TRACT	Meiotic chromosome condensation →	+0.157	+1.154	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Cotranslational protein targeting to membrane →	+0.125	+1.399	<.001	<.001	3	12
LARGE_INTESTINE	Regulation of early endosome to late endosome transport →	+0.115	+0.931	<.001	.002	3	12
SKIN	COPII-coated vesicle cargo loading →	+0.105	+0.662	.001	.003	2	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,808 associations by consensus.

Regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway by STT3A expression — OESOPHAGUS

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