STT3A-AS1

Across TCGA pan-cancer cohorts, STT3A-AS1 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated STT3A-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher STT3A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STT3A-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCS and PAAD show a favorable association.

KIRC, UCS, and KICH are the cancer types where STT3A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	IV	0.323	0.698	<.001	112	view →
UCS	DFS	Median	II,III,IV	0.548	0.177	.001	70	view →
KICH	OS	Median	All	0.682	1.000	.003	60	view →
LIHC	DFS	Tertile	All	0.445	0.628	<.001	41	view →
CESC	DFS	Quartile	II,III,IV	0.360	0.812	.002	34	view →
BLCA	OS	Tertile	IV	0.130	0.610	.001	24	view →
MESO	DFS	Quartile	All	0.218	0.384	.007	24	view →
PAAD	OS	Median	All	0.620	0.343	.006	19	view →
STAD	DFS	Quartile	II,III,IV	0.422	0.846	.005	15	view →
THYM	DFS	Median	All	0.968	0.778	.007	12	view →
COAD	OS	Median	IV	0.706	0.386	.008	12	view →
HNSC	OS	Median	III,IV	0.438	0.646	.020	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

STT3A-AS1–KIRC (DFS)

Open the KIRC breakdown →