STT3A-AS1

Across TCGA pan-cancer cohorts, STT3A-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of STT3A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where STT3A-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STT3A-AS1 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

LIHC, KICH, and THCA are the cancer types where STT3A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STT3A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.157	.001	6	view →
KICH	All	All	−0.462	.001	5	view →
THCA	All	All	−0.253	<.001	5	view →
KIRC	Male	All	−0.217	.001	5	view →
LUSC	All	II,III,IV	+0.190	.035	4	view →
PAAD	Male	All	−0.405	.007	2	view →
PRAD	All	All	+0.251	<.001	2	view →
CHOL	Male	All	+0.189	.045	2	view →
HNSC	All	All	+0.120	.025	2	view →
READ	All	All	+0.312	.049	1	view →
COAD	Male	All	+0.295	.026	1	view →
BLCA	Female	III,IV	+0.221	.008	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

STT3A-AS1–LIHC

Open the LIHC breakdown →