STRIT1

Across TCGA patient cohorts, STRIT1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STRIT1-associated genes across cancer lineages are SNRPGP7, SRIP1, and TEMN3-AS1. Each is linked with STRIT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STRIT1-to-partner and partner-to-STRIT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNRPGP7 grouped by STRIT1-low versus STRIT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRIT1→partner) and Y-score (partner→STRIT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNRPGP7 →	+0.590	+6.335	<.001	.001	3	1
UCEC	SRIP1 →	+0.237	+5.358	.001	.006	3	1
UCEC	TEMN3-AS1 →	+0.294	+5.551	.006	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

SNRPGP7 by STRIT1 expression — UCEC

Explore this box plot interactively →