STRIT1

Across TCGA pan-cancer cohorts, STRIT1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated STRIT1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher STRIT1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STRIT1 expression acts as an unfavorable survival marker, although some lineages such as STAD and OV show a favorable association.

KICH, ACC, and STAD are the cancer types where STRIT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Median	III,IV	0.343	0.942	.003	73	view →
ACC	DFS	Tertile	II,III,IV	0.179	0.595	.006	52	view →
STAD	DFS	Median	All	0.529	0.292	.002	49	view →
OV	OS	Median	All	0.379	0.280	.003	46	view →
UCEC	OS	Tertile	All	0.845	0.637	.001	42	view →
MESO	OS	Tertile	IV	0.105	0.721	<.001	39	view →
UVM	DFS	Tertile	All	0.330	0.767	.022	36	view →
LAML	DFS	Quartile	All	0.698	0.524	.018	36	view →
KIRC	DFS	Quartile	IV	0.867	0.414	.001	24	view →
UCS	OS	Median	II,III,IV	0.772	0.415	.002	24	view →
BLCA	OS	Quartile	IV	0.590	0.198	.009	22	view →
READ	DFS	Tertile	IV	0.297	0.620	.014	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

STRIT1–KICH (DFS)

Open the KICH breakdown →