STRAP

Across TCGA pan-cancer cohorts, STRAP mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated STRAP data layer compared with 23 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher STRAP mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated STRAP expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

CCRCC, LUAD, and LSCC are the cancer types where STRAP mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.585	1.000	.006	28	view →
LUAD	OS	Quartile	III,IV	1.000	0.289	.040	2	view →
LSCC	DFS	Quartile	All	1.000	0.923	.029	1	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

STRAP–CCRCC (OS)

Open the CCRCC breakdown →