STRA6

Across TCGA patient cohorts, STRA6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,308 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STRA6-associated genes across cancer lineages are GSEC, PTGS2, and GET3. Each is linked with STRA6 in more than 2 cancer types. Because this analysis shows association rather than direction, both STRA6-to-partner and partner-to-STRA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STRA6 versus GSEC in BRCA, with a Pearson correlation of -0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STRA6→partner) and Y-score (partner→STRA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	GSEC →	-0.760	-0.424	<.001	.001	3	3
LUAD	PTGS2 →	+1.787	+1.373	.003	.001	3	3
OV	GET3 →	-0.714	-0.956	.001	.001	3	2
PDAC	KPNA4P1 →	-0.500	-0.587	.005	.009	3	2
OV	RPS14P8 →	-1.977	-0.900	.001	.005	3	2
OV	NTN4 →	-1.241	-0.829	.005	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,308 associations by consensus.

STRA6 vs GSEC — BRCA

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