Q-omics provides the consensus-scored RPS14P8 profile across patient tissues and cancer cell-line models. RPS14P8 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, RPS14P8 is differentially expressed in 5, with the highest sampling consensus in KIRC. Additionally, RPS14P8 RNA expression shows 13,432 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight UVM, KIRC, and GBM as cancer lineages where RPS14P8 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for RPS14P8 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes RPS14P8 survival associations across molecular data types. RPS14P8 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible RPS14P8 RNA expression–survival associations across cancer types. High RPS14P8 expression shows unfavorable associations in UVM, ACC, BRCA and UCEC, but favorable associations in SKCM and LGG. The UVM Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify UVM as the clearest survival context for RPS14P8 RNA expression.
This table summarizes RPS14P8 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for RPS14P8. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. RPS14P8 shows lower tumor expression in BRCA and higher tumor expression in KIRC, COAD, CHOL and LIHC. The KIRC box plot shows higher RPS14P8 RNA expression in tumor versus normal tissue (log2 FC = +0.490, t-test p = .001).
This table shows molecular features associated with RPS14P8 in patient tissues and cancer cell lines. In patient samples, RPS14P8 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
