STPG2

Across TCGA cell cohorts, STPG2 mutation is significantly associated with the drug of many other genes, with 16 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STPG2-associated genes across cancer lineages are VE-822, PCI-34051, and GSK2110183B. Each is linked with STPG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG2-to-partner and partner-to-STPG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VE-822 grouped by STPG2-low versus STPG2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG2→partner) and Y-score (partner→STPG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VE-822 →	+0.611	+2.646	.033	.047	3	1
LARGE_INTESTINE	PCI-34051 →	+0.388	+2.646	.044	.047	3	1
LARGE_INTESTINE	GSK2110183B →	+0.652	+2.649	.032	.046	3	1
LARGE_INTESTINE	630600 →	+0.746	+2.649	.015	.046	3	1
LARGE_INTESTINE	Schweinfurthin A →	+0.551	+2.649	.036	.046	3	1
LARGE_INTESTINE	PRT062607 →	+0.719	+2.769	.003	.040	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

VE-822 by STPG2 expression — LARGE_INTESTINE

Explore this box plot interactively →