STPG2

Across TCGA pan-cancer cohorts, STPG2 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated STPG2 data layer compared with 5 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher STPG2 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STPG2 expression acts as an unfavorable survival marker, although some lineages such as READ and SKCM show a favorable association.

LUSC, READ, and SKCM are the cancer types where STPG2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	DFS	Median	III,IV	0.328	0.718	<.001	72	view →
READ	DFS	Median	All	0.729	0.275	<.001	54	view →
SKCM	OS	Tertile	All	0.440	0.284	.001	49	view →
THCA	OS	Tertile	All	0.939	1.000	.005	45	view →
KICH	DFS	Median	All	0.709	0.947	.008	24	view →
KIRP	DFS	Tertile	All	0.567	0.723	.003	23	view →
UCS	DFS	Median	II,III,IV	0.481	0.247	.023	14	view →
DLBC	DFS	Median	All	0.532	0.923	.013	13	view →
CHOL	DFS	Median	All	0.650	0.232	.011	9	view →
CESC	DFS	Quartile	III,IV	0.111	0.524	.026	8	view →
COAD	OS	Tertile	All	0.424	0.644	.015	8	view →
PCPG	OS	Tertile	All	0.927	1.000	.036	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

STPG2–LUSC (DFS)

Open the LUSC breakdown →