STPG1

Across TCGA patient cohorts, STPG1 protein abundance is significantly associated with the RNA expression of many other genes, with 12,836 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STPG1-associated genes across cancer lineages are ADAM28, VRK1, and USP13. Each is linked with STPG1 in more than 5 cancer types. Because this analysis shows association rather than direction, both STPG1-to-partner and partner-to-STPG1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STPG1 versus ADAM28 in GBM, with a Pearson correlation of 0.79.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG1→partner) and Y-score (partner→STPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ADAM28 →	+1.604	+0.933	<.001	<.001	3	6
LSCC	VRK1 →	-0.756	-0.531	<.001	.001	3	4
LUAD	USP13 →	-0.774	-0.458	<.001	<.001	3	4
GBM	IGKC →	+4.813	+1.206	<.001	<.001	3	4
HNSC	IGHA1 →	+2.670	+0.584	.004	.006	3	4
GBM	NVL →	-0.499	-1.225	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,836 associations by consensus.

STPG1 vs ADAM28 — GBM

Explore this scatter interactively →