STPG1

Across TCGA pan-cancer cohorts, STPG1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of STPG1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where STPG1 RNA is repressed in tumor relative to normal tissue. In most cancer types STPG1 is over-expressed in tumor, although a few such as KICH and KIRC show the opposite, repressed pattern.

KICH, HNSC, and KIRC are the cancer types where STPG1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STPG1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.781	<.001	11	view →
HNSC	Male	IV	+1.143	<.001	11	view →
KIRC	Male	II,III,IV	−0.517	<.001	11	view →
COAD	Female	II,III,IV	−0.950	<.001	10	view →
BLCA	All	III,IV	+0.904	.003	8	view →
LIHC	Male	All	+0.581	<.001	8	view →
CHOL	Male	All	+1.718	<.001	5	view →
READ	All	II,III,IV	−1.044	.002	4	view →
KIRP	All	IV	+0.297	.015	2	view →
STAD	Male	II,III,IV	+0.359	.033	1	view →
LUSC	Female	All	+0.307	.031	1	view →
LUAD	Female	All	−0.260	.023	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

STPG1–KICH

Open the KICH breakdown →