STPG1

Across TCGA patient cohorts, STPG1 mutation is significantly associated with the RNA expression of many other genes, with 3,839 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STPG1-associated genes across cancer lineages are RN7SL612P, ADAD1P2, and RNA5SP386. Each is linked with STPG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STPG1-to-partner and partner-to-STPG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL612P grouped by STPG1-low versus STPG1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STPG1→partner) and Y-score (partner→STPG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RN7SL612P →	+0.357	+5.219	<.001	.006	3	2
READ	ADAD1P2 →	+0.160	+5.219	<.001	.006	3	2
UCEC	RNA5SP386 →	+0.247	+2.198	<.001	.003	3	2
UCEC	RNA5SP413 →	+0.844	+1.599	<.001	.006	3	2
READ	PGBD4P2 →	+0.162	+6.257	<.001	.001	3	1
READ	OR52E5 →	+0.033	+5.925	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,839 associations by consensus.

RN7SL612P by STPG1 expression — READ

Explore this box plot interactively →