STON1-GTF2A1L

Across TCGA pan-cancer cohorts, STON1-GTF2A1L Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated STON1-GTF2A1L data layer compared with 18 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher STON1-GTF2A1L Mutation is associated with better disease-free survival. In most high-consensus cancer types, elevated STON1-GTF2A1L expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, LUAD, and HNSC are the cancer types where STON1-GTF2A1L Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Median	All	0.939	0.615	.013	12	view →
LUAD	OS	Median	III,IV	0.057	0.680	<.001	12	view →
HNSC	DFS	Median	All	1.000	0.315	.035	3	view →
SKCM	DFS	Median	IV	0.040	0.432	.038	3	view →
LUSC	DFS	Median	All	0.217	0.514	.043	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

STON1-GTF2A1L–UCEC (DFS)

Open the UCEC breakdown →