STOML2

Across TCGA patient cohorts, STOML2 mutation is significantly associated with the RNA expression of many other genes, with 815 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STOML2-associated genes across cancer lineages are LINC02222, RN7SL248P, and RNA5SP415. Each is linked with STOML2 in more than 1 cancer types. Because this analysis shows association rather than direction, both STOML2-to-partner and partner-to-STOML2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02222 grouped by STOML2-low versus STOML2-high in LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STOML2→partner) and Y-score (partner→STOML2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	LINC02222 →	+0.050	+6.087	.001	.002	3	2
UCEC	RN7SL248P →	+0.080	+3.606	<.001	.002	3	2
UCEC	RNA5SP415 →	+0.551	+2.351	<.001	.006	3	2
LUSC	TTTY4B →	+0.014	+7.924	<.001	.008	3	1
LUSC	MIR6744 →	+0.483	+7.924	<.001	.008	3	1
UCEC	LIN7C →	+0.605	+3.365	.004	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 815 associations by consensus.

LINC02222 by STOML2 expression — LUAD

Explore this box plot interactively →