STN1

Across TCGA pan-cancer cohorts, STN1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated STN1 data layer compared with 24 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher STN1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated STN1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, LUAD, and HNSC are the cancer types where STN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Median	All	0.972	0.671	.011	7	view →
LUAD	DFS	Median	III,IV	0.409	0.941	.010	3	view →
HNSC	DFS	Quartile	All	1.000	0.917	.048	2	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

STN1–PDAC (OS)

Open the PDAC breakdown →