STN1

Across TCGA patient cohorts, STN1 mutation is significantly associated with the immune_cell of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STN1-associated genes across cancer lineages are pDC, CD8+ naive T-cells, and Erythrocytes. Each is linked with STN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STN1-to-partner and partner-to-STN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by STN1-low versus STN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STN1→partner) and Y-score (partner→STN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	pDC →	+0.055	+3.032	.011	.018	3	2
UCEC	CD8+ naive T-cells →	+0.038	+3.202	.001	.009	3	1
UCEC	Erythrocytes →	+0.026	+2.241	.017	.031	3	1
UCEC	Th2 cells →	+0.278	+3.332	<.001	.005	3	1
UCEC	lymphatic Endothelial cells →	-0.024	-3.129	.026	.019	2	1
UCEC	Endothelial cells →	-0.044	-1.957	.010	.032	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

pDC by STN1 expression — UCEC

Explore this box plot interactively →