STN1

Across TCGA cell cohorts, STN1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STN1-associated genes across cancer lineages are C6orf118, ACSM6, and PRAMEF20. Each is linked with STN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both STN1-to-partner and partner-to-STN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C6orf118 grouped by STN1-low versus STN1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STN1→partner) and Y-score (partner→STN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C6orf118 →	+0.175	+3.793	<.001	.007	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.169	<.001	.007	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	CFHR2 →	+0.046	+4.437	<.001	.004	3	1
OVARY	LCE1D →	+0.060	+5.807	<.001	.001	3	1
OVARY	FAM170B →	+0.006	+5.807	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

C6orf118 by STN1 expression — LARGE_INTESTINE

Explore this box plot interactively →