STMN4

Across TCGA pan-cancer cohorts, STMN4 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated STMN4 data layer compared with 4 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher STMN4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated STMN4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and KIRC show a favorable association.

UCEC, SKCM, and ACC are the cancer types where STMN4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.581	0.740	<.001	108	view →
SKCM	OS	Tertile	All	0.902	0.828	.002	60	view →
ACC	OS	Median	II,III,IV	0.748	0.946	<.001	57	view →
UVM	OS	Median	III,IV	0.240	0.836	.001	35	view →
MESO	OS	Median	All	0.288	0.480	.001	31	view →
KICH	OS	Median	III,IV	0.743	0.972	.014	18	view →
KIRC	DFS	Tertile	III,IV	0.799	0.665	.024	14	view →
PAAD	OS	Median	All	0.505	0.268	.001	12	view →
BRCA	OS	Median	All	0.945	0.904	.004	12	view →
THYM	DFS	Median	All	0.820	0.972	.010	12	view →
LIHC	OS	Tertile	All	0.711	0.843	.016	11	view →
DLBC	DFS	Median	All	1.000	0.635	.019	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

STMN4–UCEC (OS)

Open the UCEC breakdown →