STMN4

Across TCGA pan-cancer cohorts, STMN4 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of STMN4’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where STMN4 RNA is repressed in tumor relative to normal tissue. In most cancer types STMN4 is over-expressed in tumor, although a few such as COAD and READ show the opposite, repressed pattern.

COAD, READ, and STAD are the cancer types where STMN4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STMN4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	−0.963	<.001	11	view →
READ	Female	All	−1.454	<.001	7	view →
STAD	All	All	−0.341	.001	6	view →
KICH	All	II,III,IV	−0.103	.002	6	view →
HNSC	Male	IV	+0.171	.026	5	view →
UCEC	All	All	−0.162	.001	4	view →
LUSC	All	II,III,IV	+0.044	.007	4	view →
THCA	All	All	+0.016	.006	4	view →
KIRC	All	All	−0.033	.003	3	view →
BRCA	All	IV	+0.329	.002	2	view →
LIHC	All	All	+0.022	.035	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

STMN4–COAD

Open the COAD breakdown →