Across TCGA patient cohorts, STK38L mutation is significantly associated with the total protein of many other genes, with 23 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK38L-associated genes across cancer lineages are mTOR_pS2448, EGFR_pY1068, and eIF4E. Each is linked with STK38L in more than 1 cancer types. Because this analysis shows association rather than direction, both STK38L-to-partner and partner-to-STK38L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK38L→partner) and Y-score (partner→STK38L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	mTOR_pS2448 →	-0.225	-3.302	.001	.010	3	2
UCEC	EGFR_pY1068 →	-0.339	-3.584	.005	.002	3	1
UCEC	eIF4E →	+0.235	+3.584	.021	.002	3	1
UCEC	JNK_pT183_Y185 →	-0.245	-2.321	.002	.034	3	1
UCEC	Ku80 →	+0.280	+2.472	.014	.011	3	1
UCEC	MEK1 →	+0.477	+2.459	.006	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 23 associations by consensus.

Exploration

STK38L survival (RNA) · tumor vs normal (RNA) · all STK38L data types