STK32C

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STK32C mutation is significantly associated with the RNA expression of many other genes, with 1,221 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK32C-associated genes across cancer lineages are RN7SL248P, OR6M1, and RNU6-831P. Each is linked with STK32C in more than 1 cancer types. Because this analysis shows association rather than direction, both STK32C-to-partner and partner-to-STK32C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by STK32C-low versus STK32C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK32C→partner) and Y-score (partner→STK32C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.059+3.059<.001.00532
COADOR6M1 →+0.630+4.324<.001.00731
COADRNU6-831P →+0.347+5.917<.001.00131
COADRNU6-1054P →+1.047+4.993<.001.00231
COADRPS15AP32 →+0.310+5.392<.001.00231
COADOR6M2P →+0.149+5.122.002.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,221 associations by consensus.

RN7SL248P by STK32C expression — UCEC

Box plot of RN7SL248P in STK32C-low vs STK32C-high samples in UCEC.

Explore this box plot interactively →

Exploration