STK32B

Across TCGA patient cohorts, STK32B mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK32B-associated genes across cancer lineages are PCNA, 4E-BP1, and Bid. Each is linked with STK32B in more than 2 cancer types. Because this analysis shows association rather than direction, both STK32B-to-partner and partner-to-STK32B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by STK32B-low versus STK32B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK32B→partner) and Y-score (partner→STK32B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.161	+1.362	.035	.037	3	3
UCEC	4E-BP1 →	+0.248	+3.321	.009	.009	3	3
COAD	Bid →	+0.129	+3.000	.021	.035	3	2
UCEC	mTOR_pS2448 →	-0.113	-1.787	.031	.026	3	2
UCEC	p27_pT198 →	+0.090	+1.662	.017	.011	3	2
UCEC	Rab25 →	-0.338	-2.459	.003	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

PCNA by STK32B expression — UCEC

Explore this box plot interactively →