STK32B

Across TCGA pan-cancer cohorts, STK32B RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of STK32B’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where STK32B RNA is repressed in tumor relative to normal tissue. In most cancer types STK32B is over-expressed in tumor, although a few such as KICH and BLCA show the opposite, repressed pattern.

KICH, BLCA, and STAD are the cancer types where STK32B tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STK32B RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	IV	−3.846	<.001	11	view →
BLCA	Male	IV	−1.950	<.001	11	view →
STAD	All	IV	−1.216	.001	10	view →
THCA	Male	III,IV	−0.915	<.001	10	view →
HNSC	All	II,III,IV	+0.788	<.001	10	view →
COAD	Female	II,III,IV	−0.560	<.001	10	view →
LIHC	Male	All	+0.297	<.001	6	view →
KIRP	All	All	−0.916	.002	4	view →
LUAD	All	All	+0.551	.001	4	view →
CHOL	All	All	+1.151	<.001	3	view →
READ	Female	All	−1.108	<.001	2	view →
PRAD	All	All	−0.234	<.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

STK32B–KICH

Open the KICH breakdown →