STK32B

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, STK32B mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK32B-associated genes across cancer lineages are OR6V1, GUCA2B, and C20orf85. Each is linked with STK32B in more than 1 cancer types. Because this analysis shows association rather than direction, both STK32B-to-partner and partner-to-STK32B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by STK32B-low versus STK32B-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK32B→partner) and Y-score (partner→STK32B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SOFT_TISSUEOR6V1 →+0.069+5.369<.001.00432
CNSGUCA2B →+0.043+4.981<.001.00832
SOFT_TISSUEC20orf85 →+0.115+5.369<.001.00431
SOFT_TISSUEOR1L4 →+0.072+5.369<.001.00431
SOFT_TISSUETBATA →+0.013+5.369<.001.00431
SOFT_TISSUEOR4D6 →+0.046+5.977<.001.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

OR6V1 by STK32B expression — SOFT_TISSUE

Box plot of OR6V1 in STK32B-low vs STK32B-high samples in SOFT_TISSUE.

Explore this box plot interactively →

Exploration