STK32A

Across TCGA patient cohorts, STK32A mutation is significantly associated with the RNA expression of many other genes, with 2,496 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible STK32A-associated genes across cancer lineages are RNA5SP436, CHAF1B, and IDI1. Each is linked with STK32A in more than 3 cancer types. Because this analysis shows association rather than direction, both STK32A-to-partner and partner-to-STK32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by STK32A-low versus STK32A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK32A→partner) and Y-score (partner→STK32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.219	+2.615	<.001	.004	3	4
UCEC	CHAF1B →	+0.550	+2.338	.002	.003	3	2
UCEC	IDI1 →	+0.582	+2.732	.001	.003	3	2
READ	OR7G2 →	+0.046	+5.653	<.001	.003	3	2
STAD	BPY2DP →	+0.331	+5.105	<.001	.008	3	2
UCEC	RNA5SP414 →	+0.477	+1.975	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,496 associations by consensus.

RNA5SP436 by STK32A expression — UCEC

Explore this box plot interactively →