STK32A

Across TCGA pan-cancer cohorts, STK32A RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of STK32A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where STK32A RNA is repressed in tumor relative to normal tissue. In most cancer types STK32A is over-expressed in tumor, although a few such as KIRC and COAD show the opposite, repressed pattern.

KIRC, THCA, and COAD are the cancer types where STK32A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STK32A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Female	IV	−1.806	<.001	12	view →
THCA	Female	II,III,IV	+2.377	<.001	11	view →
COAD	All	All	−0.310	<.001	10	view →
LUAD	Female	All	+1.212	<.001	9	view →
KIRP	All	II,III,IV	−1.044	<.001	9	view →
BLCA	All	III,IV	+1.190	.006	7	view →
LUSC	Female	II,III,IV	−1.014	<.001	7	view →
BRCA	All	III,IV	−0.844	<.001	6	view →
STAD	All	All	−0.408	<.001	6	view →
KICH	Female	All	+1.710	<.001	5	view →
READ	All	All	−0.700	.005	4	view →
CHOL	All	All	+0.955	.008	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

STK32A–KIRC

Open the KIRC breakdown →