STK32A

Across TCGA cell cohorts, STK32A mutation is significantly associated with the drug of many other genes, with 46 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK32A-associated genes across cancer lineages are Lestaurtinib, Paclitaxel, and Niraparib. Each is linked with STK32A in more than 1 cancer types. Because this analysis shows association rather than direction, both STK32A-to-partner and partner-to-STK32A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lestaurtinib grouped by STK32A-low versus STK32A-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK32A→partner) and Y-score (partner→STK32A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Lestaurtinib →	+0.505	+2.710	.043	.043	3	1
LARGE_INTESTINE	Paclitaxel →	+0.783	+2.649	.018	.046	3	1
LARGE_INTESTINE	Niraparib →	+0.464	+2.868	.005	.022	3	1
LARGE_INTESTINE	Talazoparib →	+0.771	+2.649	.006	.046	3	1
LARGE_INTESTINE	AZD7969 →	+0.465	+2.649	.042	.046	3	1
LARGE_INTESTINE	JAK_8517 →	+0.661	+2.871	.030	.021	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 46 associations by consensus.

Lestaurtinib by STK32A expression — LARGE_INTESTINE

Explore this box plot interactively →