STK32A-AS1

Across TCGA pan-cancer cohorts, STK32A-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated STK32A-AS1 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher STK32A-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated STK32A-AS1 expression acts as an unfavorable survival marker, although some lineages such as ACC and MESO show a favorable association.

UVM, CESC, and ACC are the cancer types where STK32A-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	DFS	Tertile	II,III,IV	0.330	0.856	<.001	114	view →
CESC	DFS	Tertile	II,III,IV	0.213	0.601	<.001	74	view →
ACC	OS	Tertile	All	0.839	0.419	<.001	73	view →
MESO	OS	Median	All	0.739	0.285	.002	43	view →
LUAD	OS	Median	All	0.855	0.717	.004	37	view →
LUSC	DFS	Quartile	All	0.294	0.472	.003	35	view →
LGG	OS	Median	All	0.933	0.840	.001	24	view →
BRCA	OS	Median	III,IV	0.883	0.771	.005	20	view →
UCS	OS	Median	II,III,IV	0.551	0.253	.017	16	view →
ESCA	DFS	Median	IV	0.213	0.626	.026	12	view →
KIRC	DFS	Tertile	III,IV	0.358	0.607	.005	11	view →
SARC	OS	Tertile	All	0.914	0.792	.003	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

STK32A-AS1–UVM (DFS)

Open the UVM breakdown →