STK32A-AS1

Across TCGA pan-cancer cohorts, STK32A-AS1 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of STK32A-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where STK32A-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types STK32A-AS1 is over-expressed in tumor, although a few such as COAD and BRCA show the opposite, repressed pattern.

THCA, LUAD, and COAD are the cancer types where STK32A-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STK32A-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	III,IV	+1.993	<.001	11	view →
LUAD	Female	All	+1.172	<.001	8	view →
COAD	All	III,IV	−0.293	<.001	8	view →
BLCA	Male	All	+0.898	<.001	6	view →
BRCA	All	III,IV	−0.519	<.001	6	view →
STAD	All	II,III,IV	−0.339	.001	6	view →
KIRC	All	IV	−0.339	<.001	5	view →
KIRP	Female	II,III,IV	−0.588	.016	3	view →
LUSC	Female	II,III,IV	−0.535	<.001	3	view →
HNSC	All	All	−0.077	.011	3	view →
CHOL	All	All	+0.861	.006	2	view →
READ	Female	All	−0.686	.022	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

STK32A-AS1–THCA

Open the THCA breakdown →