STK3

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, STK3 protein abundance is significantly associated with the RNA expression of many other genes, with 17,032 significant associations in total. GBM shows the largest number of these associations.

The most reproducible STK3-associated genes across cancer lineages are YWHAZ, MTDH, and MTERF3. Each is linked with STK3 in more than 8 cancer types. Because this analysis shows association rather than direction, both STK3-to-partner and partner-to-STK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STK3 versus YWHAZ in BRCA, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK3→partner) and Y-score (partner→STK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAYWHAZ →+0.805+0.529<.001<.00139
BRCAMTDH →+0.751+0.444<.001<.00137
OVMTERF3 →+0.797+0.506<.001<.00137
HNSCVIRMA →+0.557+0.308.003<.00137
OVENY2 →+0.834+0.398<.001<.00136
OVZNF706 →+0.540+0.286<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 17,032 associations by consensus.

STK3 vs YWHAZ — BRCA

Per-sample scatter of STK3 vs YWHAZ in BRCA (Pearson r = 0.50).

Explore this scatter interactively →

Exploration