STK25

Across TCGA cell cohorts, STK25 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible STK25-associated genes across cancer lineages are TBC1D21, CEACAM20, and OR6Q1. Each is linked with STK25 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK25-to-partner and partner-to-STK25 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D21 grouped by STK25-low versus STK25-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK25→partner) and Y-score (partner→STK25) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	TBC1D21 →	+0.008	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CEACAM20 →	+0.164	+3.548	<.001	.004	3	1
LARGE_INTESTINE	OR6Q1 →	+0.012	+3.700	<.001	.009	3	1
LARGE_INTESTINE	CD300H →	+0.031	+4.000	<.001	<.001	3	1
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	1
BLOOD_Leukemia	C20orf85 →	+0.036	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

TBC1D21 by STK25 expression — LARGE_INTESTINE

Explore this box plot interactively →