STK17A

Across TCGA cell cohorts, STK17A RNA expression is significantly associated with the go_rna of many other GO terms, with 5,412 significant associations in total. BONE shows the largest number of these associations.

The most reproducible STK17A-associated GO terms across cancer lineages are Cellular response to abiotic stimulus, Cellular response to environmental stimulus, and Establishment of epithelial cell apical/basal polarity. Each is linked with STK17A in more than 11 cancer types. Because this analysis shows association rather than direction, both STK17A-to-partner and partner-to-STK17A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to abiotic stimulus grouped by STK17A-low versus STK17A-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STK17A→partner) and Y-score (partner→STK17A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular response to abiotic stimulus →	+0.046	+1.007	<.001	<.001	3	12
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.046	+1.007	<.001	<.001	3	12
LIVER	Establishment of epithelial cell apical/basal polarity →	+0.240	+1.731	<.001	.002	3	11
LUNG_NSCLC_LUAD	Sympathetic neuron projection guidance →	+0.847	+1.525	<.001	<.001	3	11
BONE	Regulation of blood coagulation →	+0.262	+1.878	<.001	<.001	3	11
BONE	Negative regulation of Rho protein signal transduction →	+0.180	+1.435	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,412 associations by consensus.

Cellular response to abiotic stimulus by STK17A expression — LARGE_INTESTINE

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