STK16

Across TCGA cell cohorts, STK16 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK16-associated genes across cancer lineages are MSGN1, TAFA1, and C14orf180. Each is linked with STK16 in more than 1 cancer types. Because this analysis shows association rather than direction, both STK16-to-partner and partner-to-STK16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MSGN1 grouped by STK16-low versus STK16-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK16→partner) and Y-score (partner→STK16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MSGN1 →	+0.100	+3.930	<.001	.003	3	1
LARGE_INTESTINE	TAFA1 →	+0.329	+4.688	<.001	<.001	3	1
LARGE_INTESTINE	C14orf180 →	+0.213	+4.155	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

MSGN1 by STK16 expression — LARGE_INTESTINE

Explore this box plot interactively →