STK11IP

Across TCGA cell cohorts, STK11IP mutation is significantly associated with the RNA expression of many other genes, with 247 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible STK11IP-associated genes across cancer lineages are TRAT1, OR4C6, and IFNG. Each is linked with STK11IP in more than 2 cancer types. Because this analysis shows association rather than direction, both STK11IP-to-partner and partner-to-STK11IP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAT1 grouped by STK11IP-low versus STK11IP-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (STK11IP→partner) and Y-score (partner→STK11IP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TRAT1 →	+2.117	+3.754	.006	.002	3	3
BLOOD_Lymphoma	OR4C6 →	+0.664	+3.736	<.001	.004	3	3
BLOOD_Leukemia	IFNG →	+0.218	+3.889	<.001	<.001	3	2
BLOOD_Leukemia	FATE1 →	+0.094	+3.381	<.001	.002	3	2
BLOOD_Lymphoma	OR56A5 →	+0.071	+3.342	<.001	.008	3	2
BLOOD_Leukemia	OR2T2 →	+0.192	+3.536	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 247 associations by consensus.

TRAT1 by STK11IP expression — BLOOD_Leukemia

Explore this box plot interactively →