STK11

Across TCGA patient cohorts, STK11 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,461 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible STK11-associated proteins across cancer lineages are RAVER1, CC2D1A, and THOP1. Each is linked with STK11 in more than 4 cancer types. Because this analysis shows association rather than direction, both STK11-to-partner and partner-to-STK11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, STK11 versus RAVER1 in GBM, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (STK11→partner) and Y-score (partner→STK11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RAVER1 →	+0.339	+0.346	<.001	<.001	3	5
GBM	CC2D1A →	+0.169	+0.249	<.001	<.001	3	4
OV	THOP1 →	+0.356	+0.416	<.001	.001	3	4
BRCA	SND1 →	-0.312	-0.593	<.001	<.001	3	4
GBM	HNRNPM →	+0.198	+0.379	.003	.001	3	4
BRCA	PDK1 →	-0.576	-0.539	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,461 associations by consensus.

STK11 vs RAVER1 — GBM

Explore this scatter interactively →