STIM2-AS1

Across TCGA pan-cancer cohorts, STIM2-AS1 RNA differs between tumor and matched normal tissue in 8 of 18 cancer types tested, making tumor–normal expression one of STIM2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where STIM2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types STIM2-AS1 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

KIRC, KICH, and THCA are the cancer types where STIM2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in STIM2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	All	−0.730	<.001	11	view →
KICH	Male	All	−1.432	<.001	9	view →
THCA	Male	III,IV	−1.060	<.001	8	view →
KIRP	All	All	−0.545	.001	7	view →
UCEC	All	All	+0.546	.011	6	view →
COAD	All	All	+0.388	.003	3	view →
HNSC	Male	IV	+0.496	.013	2	view →
LUSC	All	All	+0.295	.024	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 8 strongest of 8 lineages.

STIM2-AS1–KIRC

Open the KIRC breakdown →