STIM1

Across TCGA cell cohorts, STIM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,885 significant associations in total. CNS shows the largest number of these associations.

The most reproducible STIM1-associated GO terms across cancer lineages are Negative regulation of autophagy, Viral process, and Response to starvation. Each is linked with STIM1 in more than 14 cancer types. Because this analysis shows association rather than direction, both STIM1-to-partner and partner-to-STIM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of autophagy grouped by STIM1-low versus STIM1-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (STIM1→partner) and Y-score (partner→STIM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Negative regulation of autophagy →	+0.075	+1.141	<.001	<.001	3	15
BONE	Viral process →	+0.105	+1.597	<.001	<.001	3	15
STOMACH	Response to starvation →	+0.062	+1.531	<.001	<.001	3	15
LUNG_SCLC	Enamel mineralization →	+1.461	+1.430	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Phospholipid biosynthetic process →	+0.043	+0.961	<.001	<.001	3	14
STOMACH	Cellular response to starvation →	+0.064	+1.349	.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,885 associations by consensus.

Negative regulation of autophagy by STIM1 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →